string_homology
STRING: Get homologs in specified target species
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Retrieves pairwise protein similarity scores (Smith–Waterman bit scores) for the query proteins.
- If no target species (
species_b) is provided, results are intra-species (within the query species). - To retrieve homologs in other species or clades (e.g. vertebrates, yeast, plants), specify one or more NCBI taxon IDs in
species_b. - Multiple target species are supported; ask the user to clarify if needed.
- Always report species names together with their taxon IDs.
- Bit scores < 50 are not reported.
- Results are truncated to the top 50 proteins per input protein.
Input schema
| Property | Type | Required | Description |
|---|---|---|---|
| proteins | string | yes | Required. One or more protein identifiers, separated by %0d. Example: SMO%0dTP53 |
| species | any | no | |
| species_b | any | no |
Raw JSON schema
{
"properties": {
"proteins": {
"description": "Required. One or more protein identifiers, separated by %0d. Example: SMO%0dTP53",
"type": "string"
},
"species": {
"anyOf": [
{
"description": "Required. NCBI/STRING taxon (e.g. 9606 for human, or STRG0AXXXXX for uploaded genomes).",
"type": "string"
},
{
"type": "null"
}
],
"default": null
},
"species_b": {
"anyOf": [
{
"anyOf": [
{
"type": "string"
},
{
"type": "null"
}
],
"description": "Optional. One or more NCBI taxon IDs for target species, separated by comma (e.g. 9606,7227,4932 for human, fly, and yeast)."
},
{
"type": "null"
}
],
"default": null
}
},
"required": [
"proteins"
],
"type": "object"
}